Suven provides high quality in vitro ADME and in vivo pharmacokinetics for preclinical, clinical candidate selection and drug product development.

In vitro ADME

  • Solubility, Lipophilicity, Chemical / Plasma stability
  • Permeability
  • Protein binding, blood partitioning
  • Metabolic Stability, reaction phenotyping
  • Metabolite identification
  • CYP Inhibition, CYP Induction
  • Efflux and uptake transporter assays

In vivo Pharmacokinetics

  • Site specific absorption (Single pass In situ intestinal perfusion)
  • Single Dose PK/ Multiple dosing PK
  • Bioavailability
  • CNS penetration assessment
  • Distribution and elimination studies using 14C radio ligands

PK Capabilities for Differentiated Products

  • Oral Formulations
  • Injectable Products
  • Ophthalmic Products
  • Dermal Products
  • Intranasal Products
  • PK Capabilities for Differentiated ProductsView PDF